Non-Targeted UHPLC-Q-TOF/MS-Based Metabolomics Reveals a Metabolic Shift from Glucose to Glutamine in CPB Cells during ISKNV Infection Cycle
Infectious spleen and kidney necrosis virus (ISKNV) has caused serious economic losses in the cultured mandarin fish (Siniperca chuatsi) cartoon martian with big head industry in China.Host metabolism alteration induced by disease infection may be the core problem of pathogenesis.However, to date, little is known about the disease-induced fish meta